Catchment response to precipitation is often investigated using two-component isotope-based hydrograph separation, which quantifies the contribution of precipitation (i.e., event water Qe) or water from storage (i.e., pre-event water Qpe) to total discharge (Q) during storm events. In order to better understand streamflow-generating mechanisms, two-component hydrograph separation studies…

A total of 2 to 3 million tons of spring water flushes out from the foot of Mt. Fuji, the largest volcanic mountain in Japan. Based on the concept of piston flow transport, residence time of stored groundwater at Mt. Fuji was estimated at  ∼  15–30 years by the 36Cl ∕ Cl ratio (Tosaki et al., 2011). This range, however, represents the average residence time of groundwater that was mixed…

• The internal CO₂ gradient imposed by mesophyll conductance (gm) reduces substrate availability for C₃ photosynthesis. With several assumptions, estimates of gm can be made from coupled leaf gas exchange with isoflux analysis of carbon ∆¹³C‐gm and oxygen in CO₂, coupled with transpired water (H₂O) ∆¹⁸O‐gm to partition…

How to remove the inlet on your Picarro analyzer.

Measures hydrogen peroxide levels as low as 3 ppb to help avoid oxidation and safeguard drug stability. Major pharmaceutical, CMO, and isolator companies use Picarro hydrogen peroxide analyzers in high-potency API and biologics manufacturing and in aseptic fill and finish. The PI2114 analyzer is fast and easy to use. It doesn’t need chemicals or consumables. And it requires infrequent…

Sixty-two Picarro products now available to enable fenceline monitoring for hazardous pollutants and to build complete lab solutions for isotopic analysis

Santa Clara, CA, April 20, 2021 – Picarro Inc., a leading provider of gas concentration and stable isotope analyzers and systems for science, industrial and energy…

Picarro is committed to supporting science with its advanced gas concentration and isotopic analyzers. In this webinar, we will present the latest improvements to our analyzers and share how our customers are using them in their research. Join us to learn more about (i) our major leap in increasing sample throughput while maintaining the highest precision for laser-based water isotope…

New Express and Survey modes proven to reduce measurement time of 100 samples by as much as 68 hours

Santa Clara, CA, May 4, 2021 — Picarro Inc., a leading provider of gas concentration and stable isotope analyzers and systems for science and industrial applications, today released the…

https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/rcm.9078
https://doi.org/10.1002/rcm.9078

Rationale: Oxygen and hydrogen isotopes are important…

Picarro trace gas, gas concentration, and isotopic analyzers can be swiftly purchased through government-approved site

Santa Clara, CA, June 29…

Picarro exhibits at Virtual SEMICON West with NEW high-throughput multi-port sampling system for continuous monitoring of AMC in cleanrooms. 

Santa Clara, CA — July 13, 2020 — Picarro Inc., the industry-leading provider of trace gas analyzers for a…

To improve our understanding of chlorine chemistry indoors, reactive chlorine species such as hydrogen chloride (HCl) must be analyzed using fast time-response measurement techniques. Although well studied outdoors, sources of HCl indoors are unknown. In this study, mixing ratios of gaseous HCl were measured at 0.5 Hz in the indoor environment using a cavity ring-down spectroscopy (CRDS)…

Formaldehyde (HCHO) and nitrogen dioxide (NO₂) often co-exist in urban environments at levels that are hazardous to health. There is a demand for a solution to the problem of their combined removal. In this paper, we investigate catalysts, adsorbents and composites for their removal effciency (RE) toward HCHO and NO₂, in the context of creating a pollution control…

Atmospheric sulfate aerosols have important impacts on air quality, climate, and human and ecosystem health. However, current air-quality models generally underestimate the rate of conversion of sulfur dioxide (SO₂) to sulfate during severe haze pollution events, indicating that our understanding of sulfate formation chemistry is incomplete. This may arise because the air-quality…

A monoclonal antibody drug product (DP) manufacturing process was transferred to a different production site, where aseptic filling took place within an isolator that was sanitized using vapor phase hydrogen peroxide (VPHP). A quality-by-design approach was applied for study design to understand the impact of VPHP uptake in the isolator on DP quality. A combination of small-scale and…

Isolators are commonly used in filling operations of pharmaceutical products. To ensure an aseptic inner environment, isolators are regularly sterilized with vaporized hydrogen peroxide. However, despite extensive purging with air, some residual H₂O₂ remains within the isolator atmosphere and may thus end up in the liquid pharmaceutical drug product, which subsequently…

We developed regression models for designing rapid and effective H₂O₂ decontamination processes in the manufacturing of sterile drug products such as injectables. Decontamination, which is typically performed by using H₂O₂, is a critical changeover process used to establish a sterile environment for filling products. In the process, there is a =…

As part of manufacturing a sterile drug product, we quantified the impact of H₂O₂ sorption by polymers  on the duration of aeration in pharmaceutical decontamination. Five polymers, which are typically used as materials/parts in sterile isolators, were investigated: polyethylene, polyvinyl chloride, Silicone, polyoxymethylene (POM), and chlorosulfonated…

Santa Clara – Sept. 29, 2020 – Picarro Inc., a leading provider of trace gas analyzers for a variety of air monitoring applications, is expanding its presence in Asia by opening a customer service and support office in Hwaseong, South Korea. Having sales staff, repair services, and replacement parts available locally will allow the company to better support its growing…

ChemCorrect is a postprocess software that allows you to identify contaminated samples by comparing them with standard results. It works with all the L2xxx-i isotopic water analyzers. Directions on how to use ChemCorrect can be found in the user manual.

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