The Picarro PI2124 gas concentration analyzer measures hydrogen peroxide (H₂O₂) at levels as low as 3 ppb to help prevent oxidation and safeguard drug stability. Picarro hydrogen peroxide analyzers are widely used by major pharmaceutical companies, CMOs, and isolator manufacturers in high-potency API production, biologics manufacturing, and aseptic fill and finish environments.

The PI2124 analyzer is fast, easy to use, and requires no chemicals, consumables, or wet chemistry. With infrequent calibration and minimal maintenance, it significantly lowers operating costs while delivering highly reliable performance.

Continuous, real-time H₂O₂ monitoring

• Lower Detection Limit: <3 ppb (300 seconds, 3σ)
• Precision:
  • <3 ppb + 0.1% of reading (1σ, 10 seconds)
  • <1 ppb + 0.1% of reading (1σ, 300 seconds)
• Response Time (Rise/Fall, 10–90% / 90–10%): <1 minute
• Measurement Interval: ~10 seconds
• Measurement Range: 0–100 ppm

The PI2124 is built on Picarro’s patented Cavity Ring-Down Spectroscopy (CRDS) technology, delivering exceptional precision, low drift, and long-term stability. The analyzer maintains tight environmental control with ±0.005 °C temperature stability and ±0.0002 atm pressure stability, ensuring consistent, high-quality measurements.

Designed for GMP environments, the PI2124 includes robust operation software that supports secure data handling, real-time visualization, automated data export, and comprehensive audit trails. The system is delivered with a Certificate of Compliance, and Picarro provides installation and operational qualification (IQ/OQ) documentation along with streamlined validation using commercially available surrogate gases.

With a compact footprint, ruggedized construction, and integrated external pump, the PI2124 is optimized for continuous hydrogen peroxide monitoring in sterilization and bio-decontamination processes, supporting pharmaceutical and commercial manufacturing compliance.

Learn More

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