March 18, 2020
The year was 2008. The second wave of therapeutic biological products was just around the corner. By now it was known that many of these products were susceptible to oxidative damage by residual hydrogen peroxide left over after aeration of the aseptic processing equipment and barrier system. How sensitive these products were to low concentrations of residual hydrogen peroxide was difficult to assess because there were no obvious measurement systems capable of quickly, accurately and precisely measuring vapor phase hydrogen peroxide below a few hundred parts per billion (ppb).
The most effective and valuable new therapeutic products today are biologics, including peptides, proteins, and antibody-drug conjugates (ADCs), as well as cells, cell-derived products, and gene therapies. Many of these products are susceptible to oxidative damage by trace levels of hydrogen peroxide.
March 11, 2020
Anyone who has watched a hummingbird frantically sip from a flower or feeder can appreciate how beautiful, hyperactive, and hungry these tiny birds are. It often seems that they are constantly on the move, fiendishly searching for and defending the flowers that contain the sugary nectar they depend on.
October 1, 2019
In this second part of the 2-part blog series on Real-Time Indoor Air Measurements of Ammonia, we present a short summary of House Observations of Microbial and Environmental Chemistry (HOMEChem), part of the Indoor Chem Project (https://indoorchem.org/). Enjoy!
September 5, 2019
In part 1 of this blog series, we explore how iCHEAR used a Picarro G2103 analyzer to provide real-time measurements of ammonia emissions to separate the contribution of exhaled and dermally emitted pollutants. What proportion of human emissions do you think can be measured and what proportion remain “missing”? Read on.
September 5, 2019
There are not many countries in the world left where you can truly say that they are blessed with intact native tropical forests. Of course we all know about the Amazon, but if we have a closer look it becomes clear that even the ‘Green hell’ as the Amazon basin has been labelled, is heavily affected by humans.
April 23, 2019
At Picarro, we enjoy hearing how research groups are using our systems in their projects. Christopher Hackney and Daniel Parsons from the University of Hull (UK) are working on a series of UK Research Council and Newton Fund funded projects(e.g. http://www.stelar-s2s.org ) with partners from the Universities of Southampton, Exeter (UK), Illinois (USA) and Can Tho (Vietnam) and the Southern Institute of Water Resources Research (Vietnam)on the Mekong Delta in SE Asia.
September 25, 2018
As biologics have supplanted small molecules as the dominant focus for many leading pharmaceutical companies, robust manufacturing processes for isolators and RABS continues to be an evolving process. In this environment, as the need for significantly better VHP monitoring has grown quickly, Picarro H 2 O 2 analyzers have increased in popularity.
August 29, 2018
Monitoring isotopic composition (δ18O, δD) of water vapor, precipitation and snow surface in the Antarctic region.
Anna Kozachek of the Arctic and Antarctic Research Institute (AARI), Saint Petersburg has taken time to write a description of her team’s use of the Picarro L2130 -i and L2120 -i during the Antarctic Circumnavigation Expedition (ACE) project. The main goal of the expedition was to circumnavigate Antarctica, performing oceanographic and meteorological observations along the route as well as terrestrial observations on the sub-Antarctic and Antarctic islands. Learn more about their setup and overall findings.
August 15, 2018
Investigating Experimental Priming Effects in Anaerobic Decomposition of Peats from Discontinuous Permafrost in Canada
Accelerated rates of warming and wildfires in northern regions of Canada will result in an extensive thaw of permafrost peatlands and peat plateaus. This could result in the potential release of greenhouse gases to the atmosphere. The Department of Renewable Resources at the University of Alberta, Canada have taken time to explain how they are using the Picarro G2201 -I analyzer and Small Sample Introduction Module (SSIM) to further investigate if substrate addition “primes” peat decomposition.
August 13, 2018
At Picarro, we often write about our products and applications. But we much prefer to read how our customers are using them in their research projects. Cole Brachmann , Guillermo Hernandez Ramirez , and David Hik with the Departments of Biological Sciences and Renewable Resources at the University of Alberta, Edmonton , have taken time to pen a description of their summer soil flux study. Thanks to all three for sharing their experience.
October 5, 2017
Arctic Water and Carbon Isotope Cycles from the USCG Icebreaker Healy: Chukchi Sea, Alaska July 2016
The hydrologic and carbon cycles in the Arctic are currently changing in conjunction with climatic transitions. This includes changes in sea ice extent and thickness, Arctic Ocean pH, and patterns of primary productivity and food web dynamics. Additionally, sea ice related changes in evaporation processes are influencing winter and summer precipitation regimes and broader scale climatic patterns. For example, Arctic vortex shifts allow more Arctic air to reach lower latitudes, which can result in more frequent extreme weather events in the northeast United States.
July 22, 2016
After introducing our local collaborator, Carol Kendall from the U.S. Geological Survey (USGS) in Menlo Park, to the concept of the CWS, she cooked up a great plan for us to join Brian Bergamaschi and Bryan Downing from the USGS California Water Science Center in Sacramento on one of their upcoming delta mapping trips. Delta Cruise Part I
September 21, 2015